Chromatography solvents selected by method and grade
Lotus Corporation supports HPLC, GC, LC-MS and related analytical solvent requirements for Quality Control, Analytical Development and R&D laboratories. We help procurement and laboratory teams identify the required solvent by chemical name, CAS number, grade, pack size, method and preferred manufacturer.
The correct grade matters. A solvent sold as laboratory reagent, AR, HPLC, gradient, GC or LC-MS grade may have different specifications for water, residue, acidity, UV absorbance, fluorescence, particulate matter or trace impurities. Selection should follow the instrument, detector, method and validated specification rather than price alone.
Common solvent requirements
- Acetonitrile, methanol and water for liquid-chromatography applications.
- Isopropanol, tetrahydrofuran and other method-specific HPLC solvents.
- GC and headspace-GC solvents for chromatographic sample preparation.
- LC-MS-grade solvents for mass-spectrometry workflows.
- AR, ACS, dry and extra-dry solvents for laboratory and synthesis applications.
- Application-specific acids and modifiers used in mobile-phase preparation.
- Pack-size and manufacturer-code matching for routine procurement.
What to verify before ordering
Confirm the required grade, manufacturer specification, detector or analytical technique, water limit, stabiliser requirement, pack size and packaging material. For regulated methods, changing the brand or grade may require internal assessment. If you are seeking an alternative, send the current make, code and product specification so the comparison can be performed accurately.
Genuine supply and documentation support
Lotus Corporation prioritises genuine products sourced through established principals and supply channels. For supplied products, the team can coordinate available CoA, SDS and batch information. Quality complaints are assessed against the product actually supplied by Lotus Corporation and the associated manufacturer documentation; products obtained from unrelated channels cannot be treated as Lotus-supplied material.
Storage, handling and transport
Many solvents are flammable or otherwise regulated for storage and transport. Customers should use the current manufacturer SDS, maintain compatible storage and follow applicable institutional, transport and statutory requirements. Supply feasibility and freight can depend on pack size, destination and hazardous-goods classification.
Frequently Asked Questions
Is HPLC grade the same as LC-MS grade?
No. LC-MS-grade material is typically controlled for impurities relevant to mass-spectrometry detection. Always check the product specification against the method.
Can you quote against an existing catalogue number?
Yes. Send the manufacturer, catalogue code, grade and pack size. Lotus can review the exact product or available alternatives.
Do you supply headspace-GC solvents?
Relevant GC and headspace-grade products can be reviewed based on the solvent, method, specification and preferred make.
Can different pack sizes be offered?
Available pack sizes depend on the manufacturer and product. State the required pack and whether the next suitable size may be considered.

























