Karl Fischer solutions for moisture determination
Karl Fischer titration is widely used for water determination in pharmaceutical, chemical, food, oil, polymer and research laboratories. Lotus Corporation supports requirements for Karl Fischer reagents, working media, solvents and water standards based on the titration technique, expected moisture level, sample type and instrument.
Correct reagent selection depends on whether the method is volumetric or coulometric, the expected water content, sample solubility, side reactions and instrument configuration. A familiar product name alone is not enough to confirm compatibility.
Products we can review
- One-component and two-component volumetric Karl Fischer reagents.
- Coulometric anolytes and catholytes for cells with or without a diaphragm.
- Methanol-based and methanol-free working media or solvents.
- Reagents formulated for aldehydes, ketones, oils or other challenging matrices.
- Certified water standards for titre determination, verification and instrument checks.
- Drying and auxiliary products used in moisture-analysis workflows, subject to availability.
Information to include with your requirement
State the instrument make and model, volumetric or coulometric technique, expected water range, sample type, current reagent code, preferred pack size and any methanol-free requirement. For water standards, include the nominal water content, unit, pack format and intended use.
Reagent performance and method suitability
Samples that react with iodine, sulfur dioxide or alcohols can create interference. Insoluble samples, slow water release and oven-transfer methods also need specific consideration. Laboratories should follow the validated method, reagent manufacturer's instructions and instrument recommendations. Lotus Corporation can assist with commercial product matching but does not replace method validation by the laboratory.
Documentation and storage
For supplied products, available CoA and SDS documentation can be coordinated. Reagents and standards should be stored and handled according to the manufacturer's current instructions. Open-container stability, moisture ingress and dispensing practices can affect performance, so container closure and laboratory handling are important.
Frequently Asked Questions
How do I choose between volumetric and coulometric Karl Fischer titration?
The choice primarily depends on the expected water level, sample amount, method and instrument. Coulometry is generally used for lower moisture quantities, while volumetry suits higher amounts, but the validated method governs.
Can you match my existing reagent code?
Yes. Send the make, catalogue code, instrument and sample application so that an exact or technically appropriate option can be reviewed.
Do you supply certified water standards?
Water standards for titre determination and performance verification can be offered subject to the required water level, pack format and manufacturer availability.
Are methanol-free reagents available?
Methanol-free or application-specific options may be available. Include the sample type, technique and current method requirements.

























